Which version of Roxio Toast are you using? And this is a dumb question, but do you have a DVD burner or just a CD? Current versions of toast burn DVD\'s from ISO great. What you have to do is mount the ISO, and then burn it\'s contents to DVD. You can also usually just use your player software to play the files directly on your computer. Some other PC burning application do burn directly from an ISO I believe, but don\'t quote me, I\'m a MAC guy.